Bioresorbable Vascular Scaffold; Designed To Overcome the Limitations of Metallic Drug-Eluting Stents

Bioresorbable Vascular Scaffold
Bioresorbable Vascular Scaffold

Bioresorbable Vascular Scaffold is a non-metallic mesh tube used to treat a narrowed artery but slowly dissolves once the blocked artery can re-function naturally and remains open on its own. These scaffolds are designed to provide mechanical support and drug delivery similar to the drug-eluting stent (DES), followed by complete resorption over several years. It is a type of newly invented stent and theoretically has a number of potential benefits. Bioresorbable scaffolds are designed to reduce the adverse events related to permanent metallic stents.

Most bioresorbable vascular stents are made of polylactic acid, a naturally dissolvable material that is used in medical implants such as dissolving sutures. It is similar to a stent but dissolves gradually once the blocked artery start functioning naturally again, enabling the artery to return to its natural state. They are often used to open up a blocked artery and restore blood flow and allows artery to function naturally again. These scaffolds disappear over 12 to 24 months and supports the vessel until it has the ability and strength to stay open on its own.

Bioresorbable Vascular Scaffold Market is designed to offer the same benefits as a stent while allowing for a complete resorption over several years. Clinical trials have shown that this material may result in increased patient satisfaction. Moreover, non-metallic mesh tube are designed to overcome the limitations of metallic drug-eluting stents, which permanently cage the vessel wall, thereby preventing normal coronary vasomotion, preclude bypass grafting, and can also provoke long-term foreign-body responses.

Non-metallic mesh tube get absorbed gradually, dissolves over time, and allows artery to function naturally again, similar to the way a cast supports a broken arm and is then removed. In 2016, U.S. Food and Drug Administration (FDA) approved the first fully absorbable stent to treat coronary artery disease. Absorb GT1 Bioresorbable Vascular Scaffold System (BVS), which releases the drug everolimus to limit the growth of scar tissue, is gradually absorbed by the body in approximately three years.

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