Immunohistochemistry (IHC) Is One of the Most Common Methods of Immunostaining, Used In the Treatment of Cancer

Immunohistochemistry (IHC)
Immunohistochemistry (IHC)

Immunohistochemistry (IHC) is a useful diagnostic tool for cancer research. It uses antibodies to detect proteins that are expressed in cancer cells. As a result, it can also help determine the effectiveness of treatment. The technique is fast, accurate, and easy to perform. It has also proven useful for understanding the behaviors of various diseases, as well as predicting the outcome of treatment. In addition to diagnosing cancer, immunohistochemistry can also help predict the success of a patient's treatment. In regions such as the United States, the increasing prevalence of cancer has increased the usage of treatment options such as IHC. For instance, according to the American Cancer Society, in 2020, around 1.8 million cancer cases were diagnosed in the U.S.

The basic steps of Immunohistochemistry (IHC) Market are setting up the assay, incubating the specimen for a specific amount of time (usually one hour), obtaining fluorescent labels, and staining the samples using appropriate antigens. The primary or main antibody binds to a certain epitope on the target protein. The secondary antibody is then coupled to a molecule that acts as a reporter, and a chemical substrate is used to detect the binding of the main antibody to the antigen. The result of IHC is a colored precipitate, which can be used to determine if the epitope is present in a particular tissue section.

Immunohistochemistry (IHC) uses antibodies that recognize specific antigens in tissue sections. These antibodies are highly specific and bind only the antigen of interest in each tissue section. Different detection systems are used to visualize the antibody-antigen interaction. The results of immunohistochemistry can be used to identify abnormal cells and diseases. With the help of this procedure, physicians can predict the effectiveness of treatment for patients suffering from various conditions. Further, this technique can be done at home by non-experts, who can perform this type of test for themselves.

Apart from its clinical applications, Immunohistochemistry (IHC) is a powerful research tool, which offers excellent information on the protein expression in tissue structures and isolated cells. With these techniques, researchers can also identify cellular events such as cell death and tumor growth. Moreover, it is possible to study the distribution of biomarkers and differentially expressed proteins in different tissues. Depending on the method, the sample should be properly fixed to preserve the morphology of cells and to prevent false-positive staining.

Comments

Post a Comment

Popular posts from this blog

Sarcopenia Treatment; Training and Physical Exercise Is Key to Counteract Sarcopenia

Image
Sarcopenia Treatment A primary Sarcopenia Treatment is exercise. Researchers have identified resistance training as the specific form of exercise that is most beneficial to individuals with sarcopenia. At present, resistance exercise, protein supplementation, and vitamin D have been established as the basic treatment of sarcopenia. Recent clinical trials on sarcopenia therapies such as physical exercise, nutraceutical, and pharmaceutical interventions have revealed that exercise is the only effective strategy shown to alleviate sarcopenia. Sarcopenia refers to a loss of muscle mass specifically related to aging. It's normal to lose some muscle mass as people age. Sarcopenia has been defined as an age-related, involuntary loss of skeletal muscle mass and strength. Although aging is the main cause of sarcopenia, some other factors contribute to the loss of muscle mass. Getting little or no physical activity on a regular basis puts people at an increased risk of developing sarcopenia
Read more

Bioresorbable Implants Can Also Help To Prevent Complications And Speed Up The Recovery Process

Image
Bioresorbable Implants Medical implants, either passive for structural support or for diagnosis and therapy with active electronics, are widely used in surgical applications. Although they have shown long-term biocompatibility, their removal imposes physical, biological and economical burdens on patients. To overcome this drawback, implantable devices exhibiting biodegradation in the body have been developed. These implants disappear inside the body after a certain time of use, and can be replaced with natural bone. The resorption of Bioresorbable Implants is driven by hydrolysis of the bonds linking their monomers. The amorphous portions of the polymer degrade first, while the crystalline regions remain intact and provide most of their mechanical strength. The monomers are then broken down into lactic and glycolic acids, which are converted to pyruvate and then processed through the citric acid cycle into water and carbon dioxide. The Bioresorbable Implants Market was valued at US$
Read more

Increasing Developments by Key Players Are Expected To Augment the Growth of the Global Digital Pathology Market

Image
 Digital Pathology Digital Pathology Market , by Product Type (Image Analysis Software, Scanner {Bright Field Scanner, Fluorescence Scanner}, Services {Installation & Integration, Maintenance Services, Consulting Services}), by Therapeutic Area (Oncology, Hematology, Autoimmune Disorder, Dermatology, and Others), by Technology (Immunohistochemistry, ISH & FISH, Immunofluorescence and others) End User (Pharmaceutical & Biotechnology Companies, Diagnostic Labs, Hospital Laboratories, and Others), and by Region (North America, Latin America, Europe, Asia Pacific, Middle East, and Africa)- Size, Share, Outlook, and Opportunity Analysis, 2023 - 2030. The global Digital Pathology Market is anticipated to reach an estimated value of US$ 884.4 million in 2023 and is projected to grow at a CAGR of 12.2% from 2023 to 2030. Market Overview: Digital pathology refers to the practice of digitizing glass slides containing tissue samples and analyzing them using digital imaging technology
Read more